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Hypothyroidism in particular is a well-documented risk factor for SIBO because it slows transit time throughout the entire digestive tract

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The post lists a personal or family history of medullary thyroid carcinoma or MEN2 syndrome as an absolute contraindication for semaglutide, for tirzepatide, and for oral formulations alike

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For these patients, the gap between current and optimal mitochondrial function is largest, and SS-31 bridges more of that gap