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With prolonged use, the pituitary's baseline GH production decreases a well-documented endocrinological effect

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This imbalance contributes to the increased permeability of the gut barrier, allowing the translocation of harmful bacterial products (such as lipopolysaccharides (LPS)) into the bloodstream, where they can activate the brains immune system and promote neuroinflammation, which is a major contributor to cognitive dysfunction (Guerville and Boudry, 2016

The CAS registry number for GHK-Cu is 89030-95-5