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B12 deficiency can lead to fatigue, memory issues, mood swings, and even anemia
Vitamin B12 is not naturally present in plant-based foods unless they are fortified
Vitamin B12 There is four types of parenteral Vitamin B12 available: Cyanocobalamin 100 mcg/ml and 1000 mcg/ml best used as IM to prevent rapid loss via kidneys Hydroxycobalamin IM (compounded 1000 mcg/ml or more) known as long acting B12 (binds better to plasma proteins than cyanocobalamin) Methylcobalamin IV (compounded 1000 mcg or more up to 5000 mcg/ml) Adenosylcobalamin IV Common dose is 1000 mcg IM or IV Vitamin B12 as hydroxycobalamin is synthesized exclusively by microorganisms and is found in the liver of animals bound to protein as methylcobalamin = metabolically active form of Vitamin B12 Hydroxycobalamin is a chelator of cyanide and is used in cyanide poisoning Hydroxocobalamin is most generally used for vitamin B12 replacement therapy and is considered the drug of choice for vitamin B12 deficiency by the Martindale Extra Pharmacopoeia (Sweetman, 2002) and the World Health Organization (WHO) Model List of Essential Drugs
If there is any hormonal advantage, it would almost certainly be in the context of an individualized protocol involving lifestyle, diet, and evidence-based medical treatment
B12 Shots: How to Choose When it comes to NAD+ vs
This extended half-life means the exact hour you inject matters less than consistencyinjecting at the same time weekly trains your body to expect the medication's effects
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