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mutation of the gene is associated with pseudoxanthoma elasticum and generalized arterial calcification of infancy type 2

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Pourebrahim R, Montoya RH, Alaniz Z, Ostermann L, Lin PP, Liu B, Ayoub E, Burks JK, Andreeff M

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Pre-treatment of rats with 120 g/kg DSIP 20 minutes prior to subjection to hypoxia completely inhibited these hypoxia-induced reductions in mitochondrial respiratory activity

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