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The fundamental calculation follows a simple formula

increase by ~250 mcg every 2 weeks as tolerated

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Acknowledgements The cryo-electron microscopy data were collected at the Shanghai Advanced Center for Electron Microscopy, Shanghai Institute of Materia Medica, Chinese Academy of Sciences

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In one study comparing zinc pyrithione to a strong steroid cream (betamethasone) and a non-steroid prescription cream (tacrolimus), all three treatments improved symptoms after four weeks