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doi:10.1111/j.1532-950x.2003.00515.x

Despite advances in the understanding of its clinical features, effective treatments remain elusive, necessitating further exploration of the underlying mechanisms and novel therapeutic targets

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Spermidine synthase is encoded by the SRM gene (also known as SPDSY) which is located on chromosome 1p36.22 and is composed of 8 exons that encode a protein of 302 amino acids

If you are taking a non-liposomal form, the sheer volume of the supplement can cause irritation