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One of the physiological substrates of this transporter is acetylcholine, underlying a key role in the non-neuronal cholinergic system in both physiological and pathological conditions, as testified by the occurrence of a natural mutation of OCTN1 in inflammatory conditions such as Crohns Disease (Pochini et al., 2019)
Other Trials # Other interesting and active GLP analog trials include: Parkinsons Disease (NCT03659682) Alcohol-related Liver Disease (NCT06409130) Acute Ischemic Stroke (NCT05630586) Polycystic Ovary Syndrome (NCT05646199, NCT05702905, and more) For a literature review and deeper dive on this topic focused on research, see From diabetes to diverse domains: the multifaceted roles of GLP-1 receptor agonists 7
A network meta-analysis comparing semaglutide once-weekly with other GLP-1 receptor agonists in Japanese patients with type 2 diabetes
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