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It acts as an agonist at GLP-1, GIP, and glucagon receptors to suppress appetite, delay gastric emptying, promote insulin release, and break down fats

In addition to lowering blood glucose, GLP-1RAs can increase feelings of fullness, promote weight loss, and have potential benefits in cardiovascular protection

These shifts were partially dependent on NMDA receptor and voltage-dependent Ca 2+ channel activity (Wang et al., 2013)

Circulation (2021) 143(21):e9841010