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hCiPSC treatment partially reversed this dysbiotic state, reducing the abundance of Pseudomonadota and Deferribacterota and promoting the recovery of Bacteroidota and Verrucomicrobiota

Added Collagen: Unlike the original, it now includes collagen for anti-aging and skin firmness

Their mechanism of action involves several facets: initially, they inhibit the production and release of inflammatory mediators such as prostaglandins, leukotrienes, and tumor necrosis factor, which are pivotal in the pathogenesis of DED (Sheppard et al., 2013)

Diabetes (1996) 45(1):91100.10.2337/diab.45.1.91 180 ClemmonsDR

However, unlike other GH-Secretagogues this pentapeptide doesnt release the same volumes of cortisol, acetylcholine, prolactin and aldosterone

(1) This may upregulate growth hormone (GH) synthesis, which is a hormone with catabolic potential towards fat cells, and also may possess anabolic potential via a mediator called insulin-like growth factor 1 (IGF-1) The research suggests that it may produce rapid, concentration-dependent, pulsatile GH elevations, yielding GH pulses roughly 20- to 30-fold above basal values and potentially close to other GHSs such as GHRP-6 and GHRP-2