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10.1111/dom.12811 78 PriyadarshiniM.ColeC.OroskarG.LudvikA.WicksteedB.HeC.et al (2020)

If you take it before hitting the gym or doing cardio, youre priming your body to use fat as fuel during exercise, leading to better fat burning and improved workout performance

However, it did not yield significant improvements in pain perception.[64] GLP-1 receptors have also been detected in the choroid plexus, and in a rodent model, their activation was shown to reduce cerebrospinal fluid secretion and intracranial pressure (ICP).[65] In patients with idiopathic intracranial hypertension (IIH) and obesity, exenatide, semaglutide, liraglutide have been associated with a reduction in the number of headache days, and exenatide significantly reduced ICP.[66, 67] Furthermore, animal studies have indicated potential benefits of GLP-1RAs in neuropathic pain and diabetic neuropathy, although clinical evidence remains inconsistent.[64] One study reported structural improvements in the nerves of patients with diabetic neuropathy receiving semaglutide or dulaglutide, while two other studies found no significant benefit in neuropathy symptoms with liraglutide and exenatide.[6870] Additional off-label uses under investigation include neurodegenerative disorders, polycystic ovary syndrome (PCOS), and osteoporosis

Oral semaglutide Semaglutide oral is the first oral arGLP-1

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Aunque se usan desde hace ao para tratar la diabetes tipo 2, en el ultimo ao son el tema del momento por su aplicacin para los casos de obesidad o, simplemente, para perder peso