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Key trial findings Up to 16.3% weight loss at the 180 mg dose Results measured after around 11 months of treatment Low discontinuation rates (~23%) due to side effects Phase 3 trials planned later this year These results are particularly notable because oral GLP-1 drugs have historically struggled to match the effectiveness of injectable therapies
Intramuscular injection can cause faster absorption, unpredictable medication levels, and increased side effects
It simplifies nutrition, replaces multiple supplements, and supports patients who struggle to meet protein needs through food alone
We also provide ongoing support for individuals taking GLP-1 based medications through our Check-In and Optimization sessions
Tirzepatide seems to be the better option, said Pooja Gokhale, corresponding author of the review and a doctoral student in the UGA College of Pharmacy