Sodium-glucose transport protein 2 (SGLT2) inhibitors
Safer options include medically supervised GLP-1 therapy, nutritional counseling, cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), and holistic approaches like mindfulness-based stress reduction
The focus should be on providing the body with what it needs to be healthy, rather than eliminating foods like carbohydrates
The plateau timing around week 40 to 48 is worth understanding before you start, not because its discouraging, but because framing the goal as reaching a new stable weight rather than continuing to lose makes the final phase feel like success rather than stagnation
GLP-1 receptor agonists and mental health: A systematic review of neuropsychiatric effects
Emerging agents like Tirzepatide, which activates both GLP-1 and GIP receptors, and Orforglipron, a nonpeptide oral GLP-1 agonist in phase 2 trials, further expand the therapeutic potential of this class (23)(24)