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Plasma concentrations are highest in childhood and decline with age, which is part of why GHK-Cu shows up frequently in skin-regeneration, wound-healing, and aging-biology research as both an endogenous reference compound and a candidate study tool in cell-based models
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The bee bread undergoes anaerobic lactic fermentation during the ripening process, which is caused by bacteria (e.g., Lactobacillus spp., Pseudomonas spp.) and yeasts ( Saccharomyces spp.)