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In the phase 2 randomised controlled trial (Jastreboff et al., New England Journal of Medicine , 2023), participants receiving higher doses of retatrutide achieved mean weight reductions of up to 17.5% of body weight over 24 weeks, with greater losses reported at 48 weeks
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Timing Considerations When Taking Semaglutide Blood donation requires adequate hydration, stable blood pressure, and a hemoglobin level above a minimum threshold
Will I regain weight if I stop taking a GLP-1 drug
Researchers screened 70 hypothyroid patients on tirzepatide, ultimately analyzing 17 who met strict criteria, including stable levothyroxine doses before starting tirzepatide and adequate follow-up data
Published on May 21st, 2025
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