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5-Fluorouracil: Mechanisms of action and clinical strategies

Reduces Glucose Production : Semaglutide signals the liver to produce less glucose (sugar)

doi: 10.2337/db12-0716 52 ThomasMSFernandezML

The company recommends drinking plenty of fluids to avoid this complication

Kidney transplantation in suitable patients

Current FDA labeling for semaglutide products includes warnings or precautions involving: Acute pancreatitis Acute gallbladder disease Acute kidney injury due to volume depletion Severe gastrointestinal reactions Hypoglycemia when combined with insulin or insulin secretagogues Diabetic retinopathy complications in susceptible patients Serious hypersensitivity reactions Pulmonary aspiration risk during general anesthesia or deep sedation Semaglutide labeling also contains a boxed warning regarding thyroid C-cell tumors observed in rodents