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Thyroid function tests are appropriate every 3-6 months, especially for women on thyroid replacement therapy

Lancet Gastroenterol

Regulatory and Legal Status This is one of the most important and most frequently misunderstood differences between the two compounds

In the SURPASS-2 trial, which compared it head-to-head against semaglutide 1 mg over 40 weeks, tirzepatide lowered HbA1c by about 2.0 to 2.3 percentage points across its 5, 10, and 15 mg doses, versus roughly 1.9 points for semaglutide, with greater weight loss as well

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This article explains why muscle matters, what the research shows about lean mass loss on these drugs, and the evidence-based strategies protein intake, resistance exercise, and smart monitoring that can help protect your muscle while losing weight