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Though the mechanism is still to be explored, the findings of this study, along with others (Morrison et al., 2015

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GRK2 was also shown to mediate heterologous desensitization by promoting MOR transphosphorylation upon neuropeptide FF receptor activation (Mouldous et al., 2012)

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Pregnant and nursing women known to be heterozygous for the deficiency also should avoid ingestion of drugs with oxidant potential, because some gain access to the fetal circulation and to breast milk

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