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Doxorubicin-GSH adduct formation kinetics are thermodynamically estimated from its reduction potential, while the remainder of the model is parameterised using oxygen consumption rate data, indicative of hydroquinone auto-oxidation

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Globally, pernicious anemia, a condition in which the parietal cells of the stomach fail to produce intrinsic factor, is the most common cause of vitamin B12 deficiency

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Les glutathion-S-transfrases acclrent cette raction et le GSH y met fin