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Finally, dicyclohexylcarbodiimide (DCC) effects the dehydration of a carboxylic acid and amine mixture to the corresponding amide under relatively mild conditions

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in: Journal of Molecular Biology , 267 (1997)4, 1039-1052) Previous studies of model peptides have also shown that salt bridges spaced at i,i +4 along the peptide chain are more stabilizing than those spaced at i,i +3, with a preference for the order acid-base rather than base-acid from the N- to the C- terminus

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