These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
Manish Sahni, MD, at Centra Internal Medicine The FDA has officially approved oral semaglutide for chronic weight management, marking a historic milestone in obesity medicine
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CONTRAVE is a combination of two commonly prescribed medications
Constipation on GLP-1 Therapy: Why It Should Not Be Ignored Constipation is more than an inconvenience
The medications work as a GIP and GLP-1 receptor agonists, activating the hormone receptors and working to slow digestion and, in turn, increase satiety and reduce food cravings