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Before attributing symptoms to histamine intolerance, other conditions should be excluded according to UK guidelines, including: Food allergies (following BSACI guidance) Irritable bowel syndrome (NICE CG61) Coeliac disease (NICE NG20) Inflammatory bowel disease Red flags that warrant further investigation include unintentional weight loss, gastrointestinal bleeding, persistent vomiting, and iron-deficiency anaemia

Some people may experience mild side effects such as stomach upset or allergic reactions

Uncontrolled hypertension should be stabilized before GLP-1 initiation

"Whether that is a permanent change in the structure we don't know, but it will make them look different - and of course one of the signs of melanoma is a mole or a freckle that has changed its appearance," Dr Miller said

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Researchers also suspect that the profound hormonal and metabolic changes triggered by GLP-1 drugs may play a role