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Strength, work capacity, and body fat changes usually take more time

An exceptionally low initiation rate was observed even in this potentially advantaged population suggests GLP-1 RA initiation rates in the broader Polish population may be equally concerning, if not worse

Dermatologic Dermatologic toxicity is ranked among the most frequent (40%-50%) and earliest reported (2-3 weeks) irAEs and includes rash, vitiligo (loss of skin pigment) and pruritus (itchy skin)

This would allow them to combine a monoclonal antibody with a GLP-1 agonist to address muscle mass loss, a notable side effect of all GLP-1 treatments

Am J Pediatr Hematol Oncol 1979;1:169-73

The timeline for results depends on your goals