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Xanthine oxidase (XO) inhibitors represent a prominent class of pharmaceutical agents extensively employed as anti-gout drugs

Patients were subjected to five different Cur doses (500, 1,000, 2,000, 4,000, and 8,000 mg) every day for 3 months, and data showed that Cur treatment up to 8,000 mg/day is not toxic (Hsu and Cheng, 2007)

Common injection sites include the abdomen (avoiding the area immediately around the navel), anterior thigh, or upper arm

doi: 10.1016/j.lpm.2018.03.011 177 SchmittF

In some embodiments, the otic formulation or composition comprises about 0.8% by weight of the viscosity modulating agent(s)

10.1016/j.cub.2014.03.038 Curr