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After 16 weeks of liraglutide therapy, the patient achieved a 9.7 kg weight reduction, demonstrating that GLP-1 RAs can re-induce weight loss even after prior surgical failure [68]

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The Journal of Clinical Endocrinology & Metabolism , 107(3), 852-860

For the full Phase 2 statistics including adverse event rates, discontinuation breakdown, and cohort-by-cohort numbers, see the Retatrutide Statistics 2026 data page

J Clin Med

However, its angiogenic properties raise legitimate safety considerations, suggesting that indication-specific developmentfavoring acute or localized applicationsmay be more appropriate than chronic systemic exposure