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[7] [8] Patients on clozapine should likewise avoid glycine unless supervised closely, as it may blunt clozapines efficacy

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Equalize Pressure: To make withdrawal easier and to avoid creating a strong vacuum inside the vial, first draw up an amount of air into the syringe equal to the volume of BAC water you plan to withdraw

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However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision