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State telehealth regulations (in the US) and GMC guidance (in the UK) require that remote prescribers establish a clinically appropriate relationship with the patient

Notably, the treatment preferentially preserved the inner tibial cartilage zone and was associated with a trend toward reduced osteophyte formation [139]

Those trials examined its effect on body weight and fat mass in adults with obesity

The clinical relevance of this finding may, however, be limited

Participants were aged 65 years and had a body mass index of at least 30 kg/m, or at least 27 kg/m with at least 1 obesity-related complication (without diabetes)

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