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Glutathione steps in to neutralize these unstable molecules before they can damage DNA, proteins, or cell membranes

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Data was acquired using Thermo Xcalibur 4.0 Software (Thermo Scientific, Waltham, MA USA) MS data processing and analysis were made using Skyline software (V20, MacCoss Lab, University of Washington, Seattle, WA)

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Our results in the present study show that ASA-induced mitochondrial dysfunction and oxidative stress were further augmented in GSH-depleted cells, while NAC treatment attenuated the effects of aspirin in GSH-depleted cells