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Evolving insights into the pathophysiology of diabetic neuropathy: implications of malfunctioning glia and discovery of novel therapeutic targets

However, these medications have harmful and dangerous side effects

Additionally, lacosamide, an approved drug for treating epilepsy, has also been reported to induce histone hyperacetylation via reductions of HDACs protein expressions, enhancement of histone acetyltransferase or HDAC inhibition by its metabolites [48, 49]

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So, while the explanation touches on real aspects of neuropathy and B12 deficiency, it might oversimplify or misrepresent some of the complex interactions in the nervous system

doi: 10.1155/2020/5036959 42 LiuS.XuF.WeiH.HuangC.ChenX.LianR.et al