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Finally, BDNF knockdown in the vSUB had no effect on learning and memory, as measured in the Morris water maze paradigm (Figure 4e, f)

A medical review can help identify and manage these factors

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Preprint posted online February 8, 2024

The ER stress response (UPR) is initiated and regulated by three ER sensors: inositol-requiring enzyme 1 (IRE1), double-stranded RNA-activated protein kinase R-like ER kinase (PERK), and activating transcription Factor 6 (ATF6) (Chen et al., 2023)