doi.org/10.1093/humrep/deac027 Hernndez-Camacho JD, Bernier M, Lpez-Lluch G, Navas P
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It is contraindicated in certain conditions such as active malignancy and must be used cautiously in those with diabetes, prediabetes, or a history of pituitary disease, which is why careful screening and regular monitoring are essential
In addition, polymeric poly(styrene-comaleic anhydride) (PSMA)-NPs and conjugated polymer poly[2-methoxy-5-(2-ethylhexoxy)-1,4-styreneyl](PPV) -PSMA-NPs nanoparticles prepared by nanoprecipitation have also been shown to reverse the immunosuppressive TME by reprogramming TAMs, and which can not only specifically target TAMs but also directly inhibit tumor growth by repolarizing TAMs to kill tumor M1 phenotype (60)
