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Diabetes 56:15511558 Hojberg PV, Vilsboll T, Rabol R et al (2009) Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

This is particularly meaningful from a research perspective, as elevated triglycerides represent an independent cardiovascular risk factor that is often undertreated by GLP-1 class compounds alone

In the second step, the thiol group of a cytosolic coenzyme A attacks the acyl-adenylate, displacing AMP to form thioester fatty acyl-CoA

It activates both GIP and GLP-1 receptors, which together regulate appetite, metabolism, and blood sugar more effectively than medications that focus on a single hormone

doi: 10.1038/srep27733