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The researchers concluded: Our findings suggest that co-administration of L-carnitine and synbiotic may be an encouraging therapeutic strategy for obesity and related cardiometabolic complications, possibly due to simultaneous targeting of multiple metabolic pathways, augmenting their bio-availability / function through potential complementary or synergistic mechanisms

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It also has to manage appetite, metabolic flexibility, and inflammation in a way that allows progress to continue long enough to become visible

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F., et al.(2023)

Probiotic bacteria must survive the harsh acidic environment of the stomach (pH 1.53.5) to reach the intestines where they exert beneficial effects