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While individual results vary, most people begin to see a more radiant and even skin tone after 4 to 8 weeks of consistent daily use

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Mobile phase: A mixed solution of sodium dihydrogen phosphate and sodium octanesulfonate (3.0 g of sodium dihydrogen phosphate and 1.0 g of sodium octanesulfonate, dissolved in water and diluted to 500 mL, adjusted to pH 3 with phosphoric acid) : acetonitrile = 96 : 4 (volume ratio)