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A group of studies support that an imbalance of SAMe metabolism, caused by the deficiency of B vitamins (folate, vitamin B 12 , and vitamin B 6 ), leads to decreased availability of donor methyl groups as associated with NTDs [78, 79]

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Scientific research has demonstrated glutathiones importance for humans by showing that cellular glutathione levels are an excellent predictor of life expectancy

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Effects on antioxidant biology Copper has a complex role in oxidative biology participating in both prooxidant chemistry (through copper-catalyzed reactive oxygen species generation in unfavorable contexts) and antioxidant chemistry (as the cofactor of superoxide dismutase)

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