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NHANES Survey Methods and Analytic Guidelines

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Nrf2 activators, such as sulforaphane, have shown potential in preventing cataract formation in human lens epithelial cells under oxidative stress conditions

Therefore, linker selection is not only a consideration in chemical synthesis but also an important integration of pharmacology and clinical strategy

Unlike nuclear DNA, mtDNA lacks protective histones and has limited DNA repair capacity, rendering it particularly vulnerable to genotoxic stress, such as from reactive oxygen species (ROS) generated during oxidative phosphorylation (OXPHOS) ( The mtDNA encodes 37 genes essential for mitochondrial function: 13 core subunits of the OXPHOS complexes, along with 22 transfer RNAs (tRNAs) and 2 ribosomal RNAs (rRNAs) required for their intramitochondrial translation (32, 33)