If you are losing weight at a satisfactory rate on 8mg with minimal side effects, staying at 8mg is a perfectly valid choice
Key Takeaways GLP-1 injection site reactions can include redness, itching, rash, bruising, swelling, pain, lumps, or thicker skin
Headache medication might help with the pain, but speak to a medical professional beforehand to ensure it is safe to take with a GLP-1 medication
Check out our complete 7-day GLP-1 meal plan with breakfast, lunch, dinner, and snack ideas plus a printable grocery list
Levels of circulating semaglutide determine reductions in HbA1c and body weight in people with type 2 diabetes
For type 2 diabetes , NICE guideline NG28 recommends considering GLP-1 agonists as an option when: Triple therapy with metformin and two other oral drugs is ineffective, not tolerated, or contraindicated The person has a BMI 35 kg/m (or 32.5 kg/m in people of South Asian or related ethnicity) and specific psychological or medical problems associated with obesity Insulin therapy would have significant occupational implications or weight loss would benefit other obesity-related comorbidities Treatment should be continued only if there is a beneficial metabolic response (HbA1c reduction of at least 11 mmol/mol [1.0%] and weight loss of at least 3% of initial body weight at 6 months)
