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In controlled Phase 3 trials of HUMIRA (40 mg SC every other week) in subjects with RA, PsA, and AS with control period duration ranging from 4 to 104 weeks, ALT elevations 3 x ULN occurred in 3.5% of HUMIRA-treated subjects and 1.5% of control-treated subjects

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CRC Press, Boca Raton, pp 7583 Tsai C-H et al (2018) Ocular drug delivery: role of degradable polymeric nanocarriers for ophthalmic application

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Current as of May 31, 2023

Unless there is clear evidence of primary bladder pathology (e.g., small capacity under anesthesia, Hunner lesions), patients should have a multidisciplinary evaluation including assessment for neuropathic pain and psychological profile