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Dysfunction or disruption of the redox buffer has been implicated in various diseases and the implications make GSH, GSSG, and their related systems valid and effective targets for medicinal chemistry interventions

They induce the expression of inflammation-related genes, including CCL2 and CCL7, which enhance macrophage recruitment and chemotaxis (105)

Molecule of the Month: Glutathione Transferases Glutathione transferase tags toxic molecules, making them easy to recognize and remove