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Dihexa exhibited an average intrinsic clearance (Clin) of 2.72 7/ and an average half=Hfe of 509.4 minutes

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Use caution in a patient with a history of angioedema with another DPP-4 inhibitor because it is unknown whether such patients will be predisposed to angioedema with JANUMET

Symptoms of low blood sugar may include dizziness or light-headedness, sweating, shakiness, blurred vision, slurred speech, weakness, anxiety, hunger, headache, irritability or mood changes, confusion or drowsiness, fast heartbeat, or feeling jittery

Endogenous tryptophan metabolite 5-Methoxytryptophan inhibits pulmonary fibrosis by downregulating the TGF-beta/SMAD3 and PI3K/AKT signaling pathway