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Vitamin B1 supports energy metabolism and carbohydrate utilisation

This central GIPR activity is one reason tirzepatide reduces cravings and alters food preferences in ways patients frequently describe as different from their experience with GLP-1-only agents

The primary concern centres on the lack of robust clinical data

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The field is evolving rapidly, and what was cutting-edge five years ago may be outdated by the time newer compounds complete their clinical programs