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It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF- in RAW 264.7 cells when used at a concentration of 10 M.3 GHK-Cu (10 g/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.

It may therefore be the case that EGT is required to maintain the optimal cellular redox state for high levels of gliotoxin production (Sheridan et al., 2016)