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The binding affinity of GHK for copper(II) is extremely high in the picomolar range for the apparent dissociation constant at physiological pH which means that in the presence of physiological copper, free GHK and copper-bound GHK readily interconvert with the bound form dominating

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H., Valore, E

This peptide hormone belongs to a family of gut-derived hormones that are released in response to food intake, particularly nutrients such as carbohydrates and fats