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ChaC glutathione specific -glutamylcyclotransferase 1 (CHAC1) can decrease the content of intracellular GSH to prompt ferroptosis in prostate cancer cell with increasing the sensitivity of prostate cancer cells to docetaxel [31]

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Addition of 3,000 nM of the representative dimer macrocycle, aML5-PEG3, did not prevent EGF-induced phosphorylation of EGFR (Supplementary Fig