25 A more recent Cochrane review of the pharmacologic treatment of low back pain (also not specific to lumbar spinal stenosis) found that NSAIDs, muscle relaxants, and opioids had a small effect on pain reduction, but use of muscle relaxants and opioids was complicated by a significant risk of adverse effects
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Bodyweight decreased dose-dependently, reaching up to about 8.7% in the highest survodutide group, and survodutide at doses of at least 1.8 mg weekly produced greater weight loss than semaglutides roughly 5.3%
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