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In GIP/GIPR binding models, Ile 12 , which is surrounded by hydrophilic components, 32 might not interact with GIPR
Mitchell, D
Ala 18 The mutation of GIP His 18 to Ala reinforced its insulinotropic effect
Table 1 The Peptide Sequences, Formulation Modifications, and Pharmacokinetics of GLP-1 and Dual GIP/GLP-1 Receptor Agonists
doi: 10.2337/dc19-0578 169 BornerTDe JongheBCHayesMR
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