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315 Mutation at 3p25.3 on SETD5 gene, which is expressed throughout the brain, is suggested to facilitate ID

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It is indicated for chronic weight management in adults who are overweight (have a body mass index, or BMI, of 27 kg/m or greater) and have at least one weight-related medical condition, such as high blood pressure, type 2 diabetes, or high cholesterol.It is also approved for adults with obesity (a BMI of 30 kg/m or greater)

Diabetes Care 42 , 10671074 (2019)