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JAMA 307(2):157164

In fact, it's the reason "miracle" drugs like Ozempic and Wegovy have skyrocketed in popularity

the agency does not review compounded versions of these drugs for safety, effectiveness, or quality." "First, you don't know what goes into these medications," said Dr

Phase 2 clinical trials published in the New England Journal of Medicine (2023) reported substantial reductions in body weight and improvements in glycaemic control in participants with obesity and type 2 diabetes, though these findings require confirmation in larger Phase 3 studies

All such effects are observations drawn from preclinical, in-vitro, and animal investigations