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Consistent with these findings, cell viability assays demonstrated that MAPKAPK2 knockdown further reduced the viability of PIG3V cells exposed to H 2 O 2 , whereas restoration of MAPKAPK2 expression partially rescued cell viability under the same conditions (Figure 7C)

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Interestingly, H-89 significantly increased AKT phosphorylation at Ser473 while inhibiting PKA

Allow the vial to sit for 12 minutes