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Changes can also reflect shifts in hydration, inflammation, nutrition status, mobility, comorbidities, or concurrent medications

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To develop cardiac insulin resistance, major factors such as hyperglycemia, hyperlipidemia, oxidative stress, inappropriate activation of sympathetic nervous system and the renin-angiotensin II-aldosterone system (RAAS), and dysregulated secretion of adipokines/cytokines are all significant contributors [139]

farmed), and the presence and levels of contaminants [127]