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This makes it a preferred option for research where dietary control is important
The dog was treated with S/V (20 mg/kg orally twice daily), furosemide, and spironolactone, but not with pimobendan
As a result Novo Nordisk and the National Institutes of Health funded a randomised, double-blind, controlled trial to look at the issue
doi: 10.1038/nature05859 207 Twum-AmpofoJFuD-XPassanitiAHussainASiddiquiMM
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